Scientists have solved a decade-long question about the mechanism that preserves the centromere, the hub that ensures DNA ...

The findings were published in the journal Nature. The centromere is the thinnest part of the chromosome that divides it into ...

With a few exceptions, eukaryotic chromosomes have a single centromere that ensures their accurate segregation during mitosis. Chromosomes that lack centromeres segregate randomly during mitosis ...

They found that two protein complexes work together to determine the centromere distribution during cell division: condesin II (CII) and the linker of nucleoskeleton and cotoskeleton (LINC). “The ...

To convert a piece of cloned DNA into a centromere-containing human artificial chromosome (HAC), an array of repeated LacO sequences is incorporated into the DNA. The DNA is then transfected into ...