Cell-line development may be speeded in several ways, but all lead to obtaining a clone of interest that produces protein at desired productivity and quality levels.

Mark Melville, Ph.D., senior director of bioprocess development at EPIRUS Biopharmaceuticals, notes that two main avenues to cell-line development are open to virtual companies like EPIRUS.

Scientists at FUJIFILM Diosynth Biotechnologies have transformed their cell line development processes by incorporating Cyto-Mine ®, the next-generation single-cell analysis system developed by ...

Cell line development (CLD) follows a process that has only changed slightly since it was established in the early days of biopharmaceutical development. The steps to create a stable ...

When that journey is cell line development, having the best tools can make the difference between high-yield clones or costly setbacks. Let’s unpack this. Early Chariterization is Key Cell line ...

This talk will focus on the current strategies in stable cell lines development, selection of suitable media for biologics production from cell lines and the current advances in the field of upstream ...

“In theory, we can leverage our omics discoveries and modeling to rationally design and engineer cell lines to interface with bioprocess development. With the development of CRISPR technology, it ...

Cell line development (CLD), like a work of art, requires a harmonious interplay between many disparate elements to create a cohesive whole. These elements each present their own potential issues, ...

Jason Martin is regional product manager of Cell Line, Media & Testing Solutions at Sartorius. Article details Pharmaceutical Technology Vol. 46, No. 9 September 2022 Pages: 28-29, 56 Citation When ...

Cell-line development (CLD) is an important step in the production of biopharmaceuticals for the treatment of different diseases. At this stage in the process, the cell line and clone best suited to ...

Cell-line development (CLD), from identifying a biological target to commercially manufacturing a biologic, is a long process and requires extensive planning and resources. There are a number of ...