Live-cell analysis and stem cell isolation techniques help researchers fully leverage 3D spheroid models, bridging the gap ...

The Advanced Cell Engineering and 3D Models (ACE-3M) Core provides established services offered previously by AIM and C-BASS cores plus new expanded capabilities for tumor organoids grown in 3D ...

Burst of rapid cell motion in 3D tumor model Researchers discover phenomenon to help explain cancer metastasis Date: March 16, 2022 Source: University of Göttingen Summary: Biological processes ...

Researchers from the Germans Trias i Pujol Research Institute (IGTP) have published a study in Scientific Reports that provides an analysis of three-dimensional (3D) culture techniques for generating ...

In this study, a screening was carried out utilizing patient-derived 3D spheroids (tumoroids). In addition to readouts on cell viability, the Cell Painting assay was adapted for the 3D tumor model.

For the 300,000 Americans living with the immune disease scleroderma, better treatments can't come soon enough. The rare and ...

Pairing 3D models with translational endpoints High-content imaging (HCI) is a high-resolution platform originally developed for automated imaging and analysis of 2D cell–based assays. Newer ...

Infiltrating CD8+ T cells exacerbate Alzheimer’s disease pathology in a 3D human neuroimmune axis model. Nature Neuroscience, 2023; DOI: 10.1038/s41593-023-01415-3 ...

Scientists have successfully immortalized lip cells, allowing new treatments for injuries and infections to be trialed on a clinically relevant lab-based model We use our lips to talk, eat, drink ...

More information: Yanli Wang et al, Reconstructing 3D chromosome structures from single-cell Hi-C data with SO (3)-equivariant graph neural networks, NAR Genomics and Bioinformatics (2025).

In their paper in Science Advances “ ChromoGen: Diffusion model predicts single-cell chromatin conformations,” senior author Zhang, together with co-first author MIT graduate students Greg ...

PDXO 3D Culture in Matrigel. Maintenance and/or expansion of active PDX-derived organoids growing in Matrigel. PDO and PDXO-PDX derived tumor organoid culture. Generation of tumor organoid models from ...