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Scientists are closing in on signals that may be able to coax the heart into producing replacement cardiac muscle cells. Using a zebrafish model system, researchers have identified a family of ...
In a paper published in the January 2009 issue of Circulation Research, the investigators report that pravastatin mobilizes bone marrow progenitor cells -- blood stem cells that are able to ...
During a severe heart attack many heart muscle cells die and are replaced by scar tissue to stabilize the heart wall.
Stem cell-derived heart muscle cells may fail to effectively replace damaged cardiac tissue because they don't contract strongly enough, according to a new study. This may help explain why stem ...
Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is ...
The paper's senior author, Dr. Michael Laflamme, said, "These results provide strong evidence that human cardiac muscle cell grafts meet physiological criteria for true heart regeneration.
Statins, used widely to treat elevated cholesterol, have been shown to prevent progression of coronary narrowing and to have other beneficial effects on the heart, such as reducing inflammation, that ...
The growth of the zebrafish heart from embryo to adult is tracked using colored cardiac muscle clones, each containing many cellular progeny of a single cardiac muscle cell. Here, a large clone of ...
Longeveron has licensed issued US Patent 12,168,028 B2, entitled “Methods for obtaining cardiomyogenic precursor cells” from the University of Miami New patent protects a method to derive GHRH ...
In a heartbeat, cardiac muscle cells contract to push blood out to the body, then relax to allow the heart to fill again. This is possible because muscle proteins are organized into sarcomeres, which ...
Injecting human cardiac muscle cells into monkeys that suffered heart attacks helped the animals’ damaged hearts pump blood better, researchers report July 2 in Nature Biotechnology. The treatment is ...
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