followed by cabazitaxel in the second-line setting. Efforts to enhance the efficacy of docetaxel has included a variety of biologic and radioactive agents in addition to the combination of ...

However, this problem may be overcome by new active drugs such as cabazitaxel. BMs should be distinguished from other CNS metastases. The term BM should be limited to the focal seeding of the ...

Two agents (cabazitaxel and abiraterone) are already accessible to prescribers, having shown survival benefits versus their comparators in randomized controlled trials, and other agents are ...

This trial is combining 177 Lu-PSMA-617 up to six cycles with cabazitaxel up to 12 doses, with cabazitaxel dose escalation: The primary objective was assessing the maximal tolerated dose of ...

The phase III VISION trial demonstrated rPFS and OS benefit of 177 Lu-PSMA-617 compared with protocol-permitted standard of care, leading to FDA approval in March 2022. 34 TheraP was a randomized ...

I am a Senior Research Fellow in systematic reviewing at ScHARR, University of Sheffield. I have undertaken numerous evaluations on the clinical effectiveness of a wide range healthcare technologies ...

Endoscopic augmentation of the lower oesophageal sphincter using hydrogel implants for the treatment of gastro-oesophageal reflux disease IPG222 27 June 2007 27 June 2007 Carmustine implants and ...

Background: Despite the boom in the development of cancer management in the last decade, most patients with metastatic prostate cancer (PCa) eventually progress to metastatic castration-resistant PCa ...

1Cancer Ecology Center, James Buchanan Brady Urological Institute, Johns Hopkins Medical Institute, Baltimore, Maryland. 2Cellular and Molecular Medicine Graduate Training Program, Johns Hopkins ...

Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China Breast cancer (BC) is the most common cancer in women and a leading cause of cancer-related ...