Leveraging its high accuracy and programmability, the CRISPR system emerges as a promising platform for advancing the identification of SNPs. In this study, we compared two type V CRISPR/Cas systems ...

For example, consider a CRISPR‐Cas9 gene knockout (CRISPR KO) screen in which a Cas9 nuclease is directed by a sequence‐programmable guide RNA (gRNA) to a complementary genomic target, generating ...

Meghana Keshavan covers biotech and contributes to The Readout newsletter. Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your ...

The evolution of biomedical science can be appreciated through studies of hemoglobin, the oxygen-carrying protein in red cells. Before molecular cloning, the geneticist Arno Motulsky noted ...

In February, doctors treated the infant with a breakthrough and historic CRISPR gene editing therapy, making KJ the very first patient in the world to receive this kind of personalized treatment.

This work was supported by a V Foundation grant awarded to C.S.T. (T2022-018). S.M.L. was funded by a T32 Physical Genomics Training Fellowship (T32GM142604) and the Dr. John N. Nicholson Fellowship ...

Forbes contributors publish independent expert analyses and insights. Juergen Eckhardt leads Bayer’s impact investment unit, Leaps by Bayer.

In KJ’s case, the nanoparticles specifically directed the therapy to the liver. Researchers used a CRISPR base editor to repair a typo in one baby’s gene, in this case changing an incorrect ...

“How awesome is it that we’re at this point?” said Nessan Bermingham, who co-founded and led Intellia, one of the first CRISPR companies, until 2017.