CRISPR: From Discovery To Clinic—And Charting A Path Forward
No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...
CRISPR system variant shows a novel DNA cleavage mechanism
Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...
The EMBO Journal4d
A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine
A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...
Gene editing approach sheds light on how mitochondria drive autophagy
Autophagy is the process by which cells digest and renew their internal structures, recycling damaged or malfunctioning ...
Impacts5d
Unveiling the Power of CRISPR Screening in Modern Genomics
CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...
EurekAlert!2d
Researchers at IRB Barcelona discover how mitochondria drive autophagy
Headed by Drs. Antonio Zorzano and Saska Ivanova, a study published in the journal Autophagy unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing ...
Crispr Therapeutics: Why I've Become Even More Bullish (Rating Upgrade)
Financial writer recommends Crispr Therapeutics AG as a strong buy due to cash position, drug pipeline, and promising ...
Crispr Therapeutics Q4 Earnings Review: Ignore The Lack Of Revenues, Buy The Future
Crispr Therapeutics AG has revenue declines but holds strong financials. Promising Sickle Cell therapy & 2025 data readouts ...
PharmiWeb24d
Advancing the development of CRISPR platform technologies
The Food and Drug Administration approval in December 2023 of the first CRISPR therapeutic, Casgevy to treat sickle cell, came 11 years after the discovery of the revolutionary gene-editing technology ...