This study provides valuable insights into the host's variable susceptibility to Mycobacterium tuberculosis, using a novel collection of wild-derived inbred mouse lines from diverse geographic ...

This basic research study presents useful data concerning the menstrual fluid composition and its potential for endometriosis biomarker research. However, despite solid bioinformatics analyses, the ...

Discover a study that investigated how vedolizumab affects the immune cells circulating in the blood, focusing on which ...

Highly effective treatments for HIV have existed since the mid-1990s. But while these treatments keep people healthy, we do not yet have a safe and scalable way to completely rid the body of the virus ...

As the science stands, the vast majority of the roughly eight million people in South Africa living with HIV will have to get ...

Here the authors explore how sAg impacts CD4 and CD8 T cell subsets, leading to either expansion or excessive release of pro-inflammatory cytokines and they observe that a temporary state of ...

Researchers identified a unique antibody signature against the Epstein-Barr virus protein EBNA1 that correlates with ...

Design We correlated the prognostic outcomes of HCC patients from a pembrolizumab trial (NCT03419481) with tumourous cell expressions of all HDAC isoforms by single-cell RNA sequencing. We ...

An additional and highly significant finding is that recruitment and activation of these T cell subsets by DPX was evident regardless ... and also delivers an innate immune activator and a universal ...

These drugs activate a unique and relatively abundant effector gamma delta T cell subset called Vγ9Vδ2 (Vgamma9 Vdelta2) T cells, which are the largest T cell subpopulation in healthy adults and are ...

We used the subset function to extract T cells and set the resolution to 0.4 for dimensionality reduction analysis clustering and further analysis. The cell suspensions obtained from the dissociation ...

Regenerative Medicine Advanced Therapy designation was granted to an investigational CAR-T cell therapy for some patients with renal cell carcinoma. The Food and Drug Administration (FDA) granted ...