Uppsala University Hospital-led investigators report that gene-edited donor islet cells survived 12 weeks inside a man with ...

New insights into how β-cell subtypes influence diabetes risk and how maternal diet, epigenetics, and stem cell therapies may ...

Patients with type 2 diabetes on a carbohydrate-restricted diet showed recovery in beta-cell function, researchers reported in The Journal of Clinical Endocrinology & Metabolism. “Beta-cell ...

It was accepted that beta cells could only function correctly in the presence of the other hormone-producing cells - alpha, delta and gamma cells - grouped together in islets within the pancreas.

Adults were more likely to sustain glycemic control with each 5 kg weight loss achieved at 1 year (OR = 1.25; 95% CI, 1.05-1.49) and with every one standard deviation increase in homeostasis model ...

Biomea Fusion, Inc. has presented promising clinical results for icovamenib, a novel therapy aimed at restoring beta-cell function in patients with type 2 diabetes, at the ATTD 2025 Conference.

Enhancement in beta-cell function was correlated with an increase in the expression levels of the GLP-1 receptor as well as intracellular insulin – both transcript and protein levels were increased.

“Intermittent fasting is usually thought to benefit beta cells, so we were surprised to find that young mice produced less insulin after the extended fasting,” explained lead author Leonardo Matta ...

Now, the researchers have unlocked another, even more significant function of the receptor: it binds insulin and directs its breakdown within beta cells.

These drugs, which mimic the gut hormone glucagon-like peptide-1 (GLP-1), can help treat those with type 2 diabetes by stimulating the production of insulin and improving the function of beta cells.