Introduction: Dementia with Lewy Bodies (DLB) is the second most common cause of neurodegenerative dementia after Alzheimer’s disease (AD), but the field is still lacking a specific biomarker for its ...
Caption Alpha-synuclein forms Lewy Body-like inclusions in the cytoplasm of yeast (left), but these are dissolved and alpha-synuclein returns to the plasma membrane upon expression of an ...
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DLB is named after deposits (cellular inclusions) called Lewy bodies, which are collections of an abnormal protein called alpha-synuclein. Lewy bodies are found throughout the outer layer of the brain ...
Neuronal alpha-synuclein disease (NSD) defines a neurodegenerative disorder that manifests when abnormal amounts of alpha-synuclein protein build up in neurons (Lewy bodies) and other parts of the ...
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Over time, the disease can also affect memory and lead to dementia. A similar condition called Lewy Body Dementia (LBD), ...
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Dementia with Lewy bodies (DLB) is caused by a build-up of an abnormal protein called alpha-synuclein, which clumps together to form Lewy bodies in the brain. It can have symptoms similar to those ...