Jawed vertebrates known as gnathostomes appear to be the first creatures with the synovial joints, according to Shubin. These joint cavities can be seen in cartilaginous fish such as skates or sharks.

Solute carrier family 26 member 2 (SLC26A2) is an SO42− transporter, facilitating the uptake of inorganic sulfate into cells.

aggrecan and versican. Indeed, there is evidence that, in many instances, these molecules are already chronically present in the tendon extracellular matrix (ECM) before an acute rupture. Our previous ...

The authors discovered that CS-modified proteoglycans, such as aggrecan, versican, neurocan, and brevican, concentrated on the edge of the low-grade gliomas. The CS GAGs promoted adhesion between ...

Visualization of myelin was performed using modified Gallyas stain or anti-myelin basic protein antibody (rat anti-MBP, 1:400, VWR, Germany), visualization of neuronal extracellular matrix was ...

Department of Clinical Microbiology, Umeå University, Umeå 901 87, Sweden Wallenberg Centre for Molecular Medicine (WCMM), Umeå University, Umeå 901 87, Sweden Umeå Centre for Microbial Research (UCMR ...

Objectives In this study, we employ a multiomic approach to identify major cell types and subsets, and their transcriptomic profiles within the infrapatellar fat pad (IFP), and to determine ...

In their important manuscript, Costa et al. establish an in vitro model for dorsal root ganglion (DRG) axonal asymmetry, revealing that central and peripheral axon branches have distinct patterns of ...

Objectives To determine whether the process of ubiquitination and/or activity of the 26S proteasome are involved in the induction of osteoarthritis (OA). Methods Bovine cartilage resorption assays, ...