The myocardium consists of different cell types, of which endothelial cells, cardiomyocytes, and fibroblasts are the most abundant. Communication between these different cell types, also called ...

In previous work, the team demonstrated that iPS cell-derived MSCs engineered to produce ACVR2B-Fc—a decoy receptor that binds and neutralizes excess BMP ligands—could reduce HO in FOP model mice.