For example, therapies targeting the epidermal growth factor receptor variant III (EGFRvIII) — a key protein often found in GBM cells — have shown only limited success due to the tumor’s variability.

WASHINGTON — After several weeks, the March Madness tournament finally comes to an exciting conclusion Monday evening, wrapping up only the second NCAA Tournament when all the No. 1 seeds made ...

Actress-politician Angelu de Leon expressed her dismay at the “misogynistic” remark of Pasig City congressional candidate Christian “Ian” Sia, who said that single mothers who are lonely ...

MANILA, Philippines — The clean energy unit of Meralco PowerGen Corp. (MGen) has switched on its 19.8-megawatt (MW) solar power plant in Bongabon in Nueva Ecija province. The company said ...

The carriageway upgrades are being carried on the A172 Stokesley Road, from just south of The Grove near the Rudds Arms, to the A174 junction. Work is taking place between 7pm and midnight ...

Martins et al, Enhancing anti-EGFRvIII CAR T cell therapy against glioblastoma with a paracrine SIRPγ-derived CD47 blocker, Nature Communications (2024). DOI: 10.1038/s41467-024-54129-w ...

They were believed to have gained access to the allotments from the nearby A172, a police spokesperson added. Anyone who saw any suspicious behaviour or individuals in the area between 21:00 BST ...

All three adults in the INCIPIENT trial had received radiation and chemotherapy for grade 4, recurrent EGFRvIII-positive glioblastoma. One patient — a 74-year-old man — exhibited rapid tumor ...

Glioblastoma, she knew, had a promising nail for the T-cell hammer: an antigen called epidermal-growth-factor-receptor variant III (EGFRvIII), which isn’t found in healthy brain tissue.

As specified in the protocol, eligible participants were 18 years of age or older with pathologically documented, World Health Organization grade 4, recurrent, EGFRvIII-positive glioblastoma.

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