CRISPR-Cas systems usually require the guide RNA to match up with a DNA sequence that’s some 18 to 20 genetic letters, or bases, in length. Chances are, Esvelt calculates, there’s no more than ...

Key Points: 1. CRISPR/Cas as a Diagnostic Tool The CRISPR/Cas system, known for gene editing, is now revolutionizing molecular diagnostics due to its high specificity and efficiency in recognizing ...

LIVE Symposium Wednesday, June 11, 2025 1:00 - 4:00 PM ET (10:00 AM-1:00 PM PT) CRISPR-based technologies have taken the world by storm thanks to the technique’s ability to edit nucleic acids. Today, ...

The University of Bayreuth's Biomaterials research group has, for the first time, successfully applied the CRISPR-Cas9 gene-editing tool to spiders. Following the genetic modification, the spiders ...

The cryogenic electron microscope structure of the A4p-activated (green) CalpL protein filament (violet) from Candidatus Cloacimonas acidaminovorans (PDB ID: 9EYJ). CRISPR-Cas systems help to ...

CRISPR’s Tricks: How Cas Enzymes Capture, Trim, and Integrate Foreign DNA New work from Jennifer Doudna’s lab could be useful for CRISPR-based technologies that seek to repurpose Cas1–Cas2 ...

When scientists first discovered CRISPR, the possibilities for gene editing seemed endless. But challenges remain when it comes to actually translating that discovery into a therapy that works for ...

In an extraordinary 6,000-word guest editorial in the October 2024 issue of The CRISPR Journal (a sister journal of GEN, published by Mary Ann Liebert, Inc.), Fyodor Urnov, PhD, laid out the ...

The University of Bayreuth's Biomaterials research group has, for the first time, successfully applied the CRISPR-Cas9 gene-editing tool to spiders. Following the genetic modification, the spiders ...