The NFL has released the full schedule for its Week 18 slate of games, set to take place on Saturday, January 4, and Sunday, January 5. The San Francisco 49ers will take on the Arizona Cardinals at State Farm Stadium on Sunday, January 5. Kickoff is scheduled for 1:25 p.m. PT,...

San Francisco 49ers head coach Kyle Shanahan shared the final injury report on QB Brock Purdy, TE George Kittle and others before the team's Week 18 matchup against the Cardinals and shared his vision for the 49ers 2025 offseason preparations.

Out of the postseason race, the San Francisco 49ers and Arizona Cardinals are preparing to start backups because of injuries for their season-ending matchup Sunday in Glendale, Ariz. San Francisco

The San Francisco 49ers' final game of the season in the NFL will likely be without Deebo Samuel, and Kyle Shanahan addressed the wide receiver's future.

San Francisco 49ers QB Joshua Dobbs and LB Fred Warner reacted to the 49ers season finale against the Arizona Cardinals.

Unfortunately, San Francisco 49ers' running back Isaac Guerendo was carted off the field early in the first quarter.

49ers head coach Kyle Shanahan said on Tuesday that quarterback ... Then they went three-and-out, giving the Cardinals the ball on their own 36. It didn’t take long for Arizona to get into the red zone, with a first down on the L.A. 20 with 1:12 left.

The San Francisco 49ers just lost 47-24 to the Arizona Cardinals. Here are the 49ers' grades for this performance.

San Francisco will start Joshua Dobbs in place of injured quarterback Brock Purdy when the 49ers end their season on Sunday at the Arizona Cardinals. 49ers coach Kyle Shanahan announced

San Francisco 49ers head coach Kyle Shanahan spoke with reporters after Friday's practice as the team prepares for its season finale, a Week 18

The wide receiver took a few knocks in the defeat to the Lions on New Year’s Eve. He missed all of the Niners' practices last week.