Types of MS. 3. Klistorner S, Barnett MH, Parratt J, Yiannikas C, Graham SL, Klistorner A. Choroid plexus volume in multiple sclerosis predicts expansion of chronic lesions and brain atrophy.

The choroid: This is a layer of blood vessels that deliver oxygen and nutrients to the eye. Around 90% of UMs begin in the choroid.

Choroid plexus tumors develop in the choroid plexus. They often form within the brain’s ventricles. They may also form in other areas of the central nervous system (CNS).

Klistorner S, Barnett MH, Wang C, Parratt J, Yiannikas C, Klistorner A. Longitudinal enlargement of choroid plexus is associated with chronic lesion expansion and neurodegeneration in RRMS patients.

Uveitis refers to inflammation of the uvea (composed of the iris, ciliary body, and choroid), but inflammation may also involve adjacent structures (e.g., the vitreous humor and retina).

Protective borders between the brain and the blood weaken with age. This includes the barrier formed by tightly linked epithelial cells in the choroid plexus, which generates cerebrospinal fluid. In ...

Journal reference: Huang, L., et al. (2023) Dynamic human retinal pigment epithelium (RPE) and choroid architecture based on single-cell transcriptomic landscape analysis.

Background: Choroid plexus carcinomas (CPC) are highly malignant, early childhood cancers in which the loss of TP53 function is a central element of their development and defines unfavorable disease.