"Prime editing is a promising approach because, in theory, we can directly correct disease mutations to specific healthy DNA sequences of our choosing," said co-corresponding author Jonathan Yen ...

When the normal DNA sequence in an individual changes or mutates it can cause disease. The mutation may involve multiple genes and may be caused by environmental factors, or there may be ...

Sequencing of the DNA isolated from the patient's normal tissue serves as a reference for somatic analysis and allows accurately distinguishing somatic variants in tumor sequencing data. The normal ...

The findings were published today in Nature Biomedical Engineering. Scientists have rapidly developed technologies to edit DNA, including Cas9 nucleases and base editors, to treat genetic diseases.

Scientists have rapidly developed technologies to edit DNA, including Cas9 nucleases and base editors, to treat genetic diseases. The study's researchers demonstrated how a "third-generation ...