Synlogic Doses First Patient in Phase 1b/2a Trial of SYNB1020 for Treatment of Hyperammonemia in Patients with Cirrhosis – First clinical trial of a Synthetic Biotic™ Medicine in patients – ...

We thank Harold Pupko for raising several relevant points concerning our article.1 Valproate-induced hyperammonemic encephalopathy is a well- described phenomenon, but its precise incidence is unknown ...