Using a novel method that gives a readout of which proteins are in specific locations within cells, UT Southwestern Medical ...

"It really nicely revealed all the sequence and dependence of very well known biochemical proteins in the focal adhesions, and they act as a seed for the oldest mechanosensitive protein recruitment ...

Holmen and her team first examined what causes melanoma cells to spread to the brain and identified focal adhesion kinase (FAK) as a potential target for new therapies. FAK is an enzyme that regulates ...

Maher, P. A. et al. Phosphotyrosine-containing proteins are concentrated in focal adhesions and intercellular junctions in normal cells. Proceedings of the National Academy of Sciences 82 ...

Intercellular adhesion can be mediated by adherens junctions, tight junctions and desmosomes, whereas cells can interact with extracellular matrix molecules through focal adhesions. Capillary loop ...

Holmen and her team first examined what causes melanoma cells to spread to the brain and identified focal adhesion kinase (FAK) as a potential target for new therapies. FAK is an enzyme that regulates ...