DENVER — There may be a link between migraine and clinical endocannabinoid deficiency, a speaker said at the American Headache Society’s annual scientific meeting. “That has really come from ...

Twenty-some years ago, Dr. Ethan Russo coined the term endocannabinoid deficiency to describe the phenomena. Cannabinoids play a critical role in maintaining balance in our bodies.

Patients suffering with migraines, particularly women, may have an endocannabinoid deficiency. Preclinical animal studies have provided evidence that supports the use of CBD in migraine models.

The endocannabinoid system (ECS) is an internal signaling system present in every animal except insects and has a long evolutionary history, which helps explain its importance.

In his research, he posits that endocannabinoid deficiency could be the underlying cause of numerous conditions, including depression, and that cannabis can play a crucial role in addressing this ...