Under standard conditions, they are very similar, because electron affinity tends to be very small. As a result, chemical hardness tends to be neglected.

Safer fluorinating reagents and access to GMP fluorination capabilities remain challenges in API synthesis. Due to its high ionization potential, electron affinity, and electronegativity, fluorine is ...

Due to its high ionization potential, electron affinity, and electronegativity, fluorine is a highly electron withdrawing substituent. In addition, fluorine-carbon bonds are much stronger than ...