Mass Eye and Ear research shows the viral vector Anc80L65 efficiently transferred genetic cargo into the inner ear of nonhuman primates via a specialized surgical procedure, paving the way for a ...

The vector that transfers the gene therapy into the inner ear is called Anc80L65, which is an AAV first created in the laboratory of Dr. Vandenberghe and was previously shown in mouse studies to ...

In a groundbreaking development that could herald a new era in the treatment of inherited deafness, a recent clinical trial has shown remarkable success in restoring hearing and speech in children.

Next, they loaded this base editing tool onto AAV-Sia6e, which has high infection tropism for inner ear cells and developed an all-in-one AAV vector for inner ear genome editing.

Army surgeons successfully transplanted a new ear "grown" inside the patient's forearm. Doctors at William Beaumont Army Medical Center in El Paso, Texas performed a total left ear reconstruction ...

The ear was constructed from her own cells as a mirror replica of her other ear. Outside experts said it is the first time that 3D-printed tissue had been implanted into a human body.