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Working as part of a public program to screen compounds to find potential medicines and other biologically useful molecules, scientists from The Scripps Research Institute and Massachusetts ...

These non-addictive class of compounds could combat the opioid pain reliever addiction and overdose problems that have contributed to the nation’s opioid epidemic. Opioids are a class of drugs that ...

"This new class of compounds stop cancer cells dividing and proliferating by switching off their ability to continue the cell cycle," says Anne Voss, co-lead researcher on the study.

Methods and Results: Virtual docking was performed on 21 compounds, selected based on their affinity for the fenestrations in Nav1.5, which included a class of sulfonamides and carboxamides we ...

And in doing so, they have discovered a new class of compounds in a disease-causing fungus, Aspergillus flavus, that the group says show potential as antileukemia drug candidates (2025, DOI: 10. ...