Embryonic development, lengthening, and repair of most bones proceed by endochondral ossification, namely through formation of a cartilage intermediate. It was previously demonstrated that adult human ...

Collectively, our data implicate endochondral ossification, bone formation that proceeds through a cartilage intermediate, as a requirement for adult HSC niche formation.

The cellular mechanisms of cartilage-bone replacement in endochondral bone formation, in mandibular condylar heads, are poorly understood. In particular, there is no definitive evidence indicating ...

The preprogrammed mechanism of bone formation a) primary ossification (embryonic) b) secondary ossification (postnatal). Credit: Bone Research, doi: 10.1038/s41413-018-0021-z ...

Bone formation can occur through two distinct pathways, namely, endochondral ossification and intramembranous ossification. 1,2 During development of some skull and facial bones or during bone ...

Wnt signaling plays a critical role in bone formation, homeostasis, and injury repair. Multiple cell types in bone have been proposed to ... Schell H, et al. Macrophages in Bone Fracture Healing: ...

Conclusions The analysis for parameters of endochondral ossification (like the hypertrophy markers Runx2, COL10 and MMP13) or of the wnt pathway (ß-catenin, DKK-1 and Sclerostin) revealed the absence ...

Embryonic development, lengthening, and repair of most bones proceed by endochondral ossification, namely through formation of a cartilage intermediate. It was previously demonstrated that adult human ...