Novel ferritin-based siRNA delivery system shows promise for targeted glioblastoma therapy
A new study led by Profs. Fan Kelong and Yan Xiyun from the Institute of Biophysics of the Chinese Academy of Sciences ...
Nature19y
siRNA design including secondary structure target site prediction
the design tool allows the user to directly order the siRNA with a simple mouse click. Elbashir, S.M. et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells.
Business Wire14d
Arrowhead Pharmaceuticals Showcases Two Clinical-Stage RNAi-Based Candidates to Treat Obesity and Metabolic Diseases
Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced presentation of preclinical data supporting the advancement of two first-in-class clini ...
Nature1d
RNAi articles from across Nature Portfolio
RNAi (RNA interference) is a biological process in which RNA molecules—microRNA (miRNA) and small interfering RNA (siRNA)—inhibit gene expression, typically by binding to messenger RNA (mRNA ...
Business Wire1mon
Atalanta Therapeutics Closes Oversubscribed $97 Million Series B Financing to Advance Two RNAi Therapies for CNS Diseases to Clinical Trials
“Atalanta’s di-siRNA technology has shown promising ability ... intractable diseases of the central nervous system using RNA interference. Atalanta’s unique platform of divalent small ...
Business Insider24d
Arrowhead presents preclinical results on ARO-ALK7
Arrowhead (ARWR) announced preclinical results on ARO-ALK7, the company’s investigational RNA interference therapeutic ... Co-treatment of tirzepatide and ALK7 siRNA had additive effects on ...
Yahoo Finance24d
Arrowhead Pharmaceuticals Presents Preclinical Data on ARO-ALK7 for Treatment of Obesity
February 25, 2025--(BUSINESS WIRE)--Arrowhead Pharmaceuticals, Inc. (NASDAQ: ARWR) today announced preclinical results on ARO-ALK7, the company’s investigational RNA interference (RNAi ...