Study: Antibody Attributes that Predict the Neutralization and Effector Function of Polyclonal Responses to SARS-CoV-2.Image Credit: Kateryna Kon / Shutterstock.com. This news article was a review ...

Antibodies function through fragment antigen-binding (Fab) and fragment crystallizable (Fc) domains that induce neutralizing and non-neutralizing functions, respectively.

This doesn't necessarily mean that neutralizing antibodies are solely providing the protection; it could be that they correlate with some other aspect of protective immune function.

In addition to blocking the entry of virus into cells, antibodies can harness immune effector functions. For example, a non-neutralizing antibody is included in a monoclonal antibody cocktail ...

Broadly neutralizing anti-HIV-1 antibodies tether viral particles at the surface of infected cells. Nature Communications , 2022; 13 (1) DOI: 10.1038/s41467-022-28307-7 Cite This Page : ...

Researchers demonstrated that SARS-CoV-2 infection induces polyfunctional antibodies. Beyond neutralization, these antibodies can activate NK cells or the complement system, leading to the ...

Thursday, July 25, 2024. News & Perspective Drugs & Diseases CME & Education Video Decision Point Drugs & Diseases CME & Education Video Decision Point ...

These findings demonstrate that these powerful antibodies exhibit different antiviral activities in addition to neutralization. The study is published in the February 2, 2022 issue of Nature ...

Teams at the Institut Pasteur, CNRS, Vaccine Research Institute (VRI) and Université de Paris have discovered a new function of anti-HIV-1[1] antibodies by applying cutting-edge microscopy techniques ...