Hosted on MSN3mon
Delivering mRNA and RNAi-based therapies in single treatment could combat complex diseases
The success of COVID-19 vaccines has highlighted the potential of mRNA-based therapies, which selectively manipulate how genes relay a function. RNA interference (RNAi), meanwhile, is a natural ...
The Scientist4mon
Gene Silencing with RNA Interference
1 This means miRNA guides can target any mRNA with homology to its seed region, even if the rest of the sequence is not a match. This promiscuous binding activity means that miRNA can act on many ...
Nanowerk10mon
RNA Interference (RNAi): A Powerful Tool for Gene Silencing and Therapeutic Applications
siRNAs are 21-25 nucleotide dsRNA molecules that are perfectly complementary to their target mRNA. They are derived from long dsRNA precursors, which can be produced endogenously or introduced ...
Nature6d
RNAi articles from across Nature Portfolio
RNAi (RNA interference) is a biological process in which RNA molecules—microRNA (miRNA) and small interfering RNA (siRNA)—inhibit gene expression, typically by binding to messenger RNA (mRNA ...
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New Era of Combined mRNA and RNAi Therapies
The success of COVID-19 vaccines has revealed the potential of mRNA-based therapies, which selectively alter how genes relay a function. On the other hand, RNA interference (RNAi) can negate the ...