If fatty liver progresses to non-alcoholic steatohepatitis (NASH), chronic inflammation and scarring may lead to liver ...

During this stage, damaged liver cells are gradually replaced with scar tissue that cannot perform normal functions. The development of fibrosis follows a predictable pattern.

Liver cells, so-called hepatocytes, make up about 60 percent of the total cell number of the organ. They have important metabolic tasks and are active in detoxification and metabolism.

In addition, they discovered that Kupffer cells, immune cells residing in the liver, act as "dual-function regulators" that can either promote or suppress inflammation through interactions with ...

After the cells differentiated through this method, the organoids began to show all major functions of the liver, producing compounds including glucose, urea, bile acid, cholesterol and triglycerol.

Hepatic stellate cells (HSCs) are activated to heal the liver when it has a lesion (such as fibrosis or fatty liver); their function is to protect the liver by producing an extracellular matrix ...