Oral wounds heal without a trace, but skin scrapes don’t. Scientists decoded molecular players that drive scarless healing, ...

University researchers have developed a new connective tissue model to study disorders like fibrosis, a type of scarring that occurs when damage to the body causes normal tissue to be replaced by hard ...

The fibrous proteins and ground substance produced by fibroblasts are what constitute the extracellular matrix (ECM), which makes up the bulk of connective tissue. The ECM has many roles within ...

Pancreatic cancer cells are known for being hard to treat, partly because they change the environment around them to block ...

During a severe heart attack many heart muscle cells die and are replaced by scar tissue to stabilize the heart wall. Connective tissue cells, known as fibroblasts (FB), are the dominant cell type in ...

Fibroblasts play a central role in maintaining healthy tissue structures, as well as in the development and progression of diseases. For a long time, these specialised connective tissue cells were ...

University of Missouri-Columbia. "Stem Cells Created From Pigs' Connective Tissue Cells." ScienceDaily. ScienceDaily, 26 June 2009. <www.sciencedaily.com / releases / 2009 / 06 / 090625141508.htm>.

Central nervous system fibroblasts are found in the meninges (protective membranes surrounding the CNS), the connective tissue of the choroid plexus (which produces the cerebrospinal fluid), and ...

Researchers at the University of Zurich have now developed an immunotherapy that specifically targets the cause – activated fibroblasts – while leaving normal connective tissue cells unharmed.

More information: Katarzyna M. Sitnik et al, Fibroblasts are a site of murine cytomegalovirus lytic replication and Stat1-dependent latent persistence in vivo, Nature Communications (2023).

Gabrielle Kardon and colleagues present a detailed study of diaphragm development in mice. They show that migration of connective tissue fibroblasts derived from the pleuroperitoneal folds ...

Published online June 28 in the Proceedings of the National Academy of Sciences, the new analysis found that lumican, a protein-sugar combination (proteoglycan) secreted by fibroblasts, and known ...