There are five main types (isotypes) of antibodies, each with distinct structures and functions: IgG, IgM, IgA, IgE, and IgD. Illustration of the five major antibody (immunoglobulin) types ...

since it is more active than other antibody types. However, the reason why it is more active had not been determined. What was known, however, is that the structure between the antibody arms ...

To overcome that limitation, MIT researchers have developed a computational technique that allows large language models to predict antibody structures more accurately. Their work could enable ...

Although their role is universal, antibody structure varies in different animals ... and they are likely to encounter different types of antigens compared to humans" said Mengfan Lyu, a graduate ...

Researchers show that analyzing the 3D shapes of antibodies, not just their genetic sequences, can better group functionally ...

They observed that the 9D2 antibodies form a five-unit cluster, known as a pentameric structure, that binds to CADM1. This large structure prevents a type of cell-cell interaction known as trans ...

Although their role is universal, antibody structure varies in different animals ... and they are likely to encounter different types of antigens compared to humans” said Mengfan Lyu, a graduate ...