Here, the potential for gut microbial-associated metabolites to impact on host drug metabolism and toxicity was explored using a novel exploratory pipeline. Candidate microbial metabolites were ...

Xenobiotic: A chemical compound that is foreign to a living organism. Phase I Metabolism: The initial enzymatic modification of compounds, primarily including oxidation, reduction or hydrolysis ...

Pathological characteristics, survival, and risk of breast cancer associated with estrogen and xenobiotic metabolism polymorphisms in Mexican women with breast cancer O. C. Martínez-Ramírez, C. Castro ...

Reference: Husain I, Gurley BJ, Kothapalli HB, et al. Evaluation of bioaccessibility, metabolic clearance and interaction with xenobiotic receptors (PXR and AhR) of cinnamaldehyde. Food Chem: Mol Sci.

Xenobiotic metabolism in human skin is a multifaceted process involving a network of phase I and phase II enzymatic pathways that modulate the biotransformation of externally applied chemicals ...