The matriarch of the Shepherd family ... revealing that Meredith's pregnant with Derek's baby. Liz is played by actress Neve Campbell, best-known for her roles in Party of Five and the Scream ...

Dr. Paul Castello, played by Mike McColl ... The seizures stop, and neurosurgeon Amelia Shepherd (naturally, one of Derek Shepherd’s sisters) takes him in for a head CT. The surgeons determine ...

And maybe put on some "Chasing Cars." Patrick Dempsey, who played Dr. Derek "McDreamy" Shepherd on ABC’s medical mainstay "Grey’s Anatomy" for more than 10 seasons, appeared at the end of ...

In arguably his most beloved and well-known role, this year’s Sexiest Man Alive played Dr. Derek Shepherd on Grey’s Anatomy for 11 seasons before his character’s heartbreaking death.

Addison Montgomery used to be married to Derek Shepherd on ‘Grey’s Anatomy ... Oceanside Wellness Group in Los Angeles. Her story played out in Private Practice. Addison did go on to ...

This is the fourth sister of Derek Shepherd, who was one of the main characters on the show for a number of years. Derek was played by Patrick Dempsey and earned the nickname McDreamy. Previously ...

that of Derek Shepherd, also known as "McDreamy," played by Patrick Dempsey. Dempsey had started throwing "diva-like fits," and a "tension" had developed between him and costar Ellen Pompeo ...

Kate Walsh played Derek Shepherd's ex-wife, Dr. Addison Montgomery, on the series from 2005-2012 Georgia Slater is a staff editor on the Parents team at PEOPLE. She has been working at PEOPLE ...

In case you forgot, the wonderful Tyne Daly played Derek’s mother for ... so maybe Teddy will come back to say goodbye to Derek. Hopefully if Liz Shepherd does return, Neve Campbell will reprise ...

Grey's Anatomy's Halloween episode surprised fans with a touching scene remembering the late Derek Shepherd ... a text from Cristina Yang, who was played by Sandra Oh during the first 10 seasons ...

The Matriarch of the Shepherd family ... revealing that Meredith's pregnant with Derek's baby. Liz is played by actress Neve Campbell, best-known for her roles in Party of Five and the Scream ...