Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing ...

Building proteins RNA splicing, a process discovered in the late 1970s, allows cells to precisely control the content of the mRNA transcripts that carry the instructions for building proteins.

Adrian R. Krainer has been awarded the 2025 Heinrich Wieland Prize for his pioneering RNA research that led to the ...

A group of Australian scientists has uncovered a new way to fight some of the toughest cancers by targeting an overlooked ...

Vigeneron GmbH has received IND approval from the FDA for VG-801, a novel mRNA trans-splicing gene therapy to treat Stargardt disease and other retinal dystrophies associated with mutations in the ...

The single strands of messenger RNA need to be precisely spliced to deliver instructions from our genes to the cell’s protein-making machinery. To carry out all of life’s functions, proteins must be ...