Parathyroidectomy had no significant impact on long-term kidney function among older adults with primary hyperparathyroidism, but if done early, it could preserve function in those aged younger ...

Parathyroid hormone levels decreased only in the surgery group from baseline to 10 years (mean difference, –4.64 pmol/L; P < .001), with no difference in the observation group.

Completing an intra-operative parathyroid hormone assay after removing the adenoma will confirm that the abnormal parathyroid tissue has been adequately resected and that full exploration of the neck ...

Parathyroidectomy was also associated a 41% decreased risk of cardiovascular mortality in studies including nearly 10,000 patients. Adverse events were inconsistently reported.

In older adults with primary hyperparathyroidism, parathyroidectomy procedure didn’t have any effect on kidney function. The study is published in Annals of Internal Medicine.

In women with primary hyperparathyroidism, parathyroidectomy increases skeletal muscle strength and volume and triggers gene expression changes that resemble those seen after an exercise regimen.

In a retrospective cohort study of 3008 patients (2749 on hemodialysis and 259 on peritoneal dialysis) using US Renal Data System data from 2015 to 2018, Mark D. Danese, PhD, MHS, of Outcomes ...

However, early parathyroidectomy may preserve kidney function in patients younger than 60 years of age with primary hyperparathyroidism. The study is published in Annals of Internal Medicine.

Background: Human parathyroid hormone (hPTH) (1–34) was approved in 2004 for the treatment of severe osteoporosis. Members of the Osteoporosis Canada clinical guidelines committee conducted a ...

Early parathyroidectomy was, however, associated with a reduced adjusted risk of this decline in kidney function in patients with newly diagnosed PHPT who were younger than age 60.

Parathyroidectomy and the Development of New Depression Among Adults With Primary Hyperparathyroidism Journal: JAMA Surgery Published: 2024-09-05 DOI: 10.1001/jamasurg.2024.3509 Affiliations: 5 ...