Focal adhesion (FA) proteins may be critical elements in the production of dystrophic neurites in Alzheimer's disease, according to research presented in the January 15 Journal of Neuroscience. Recent ...

This method combines micropatterning of elastomer substrates and fluorescence imaging of focal adhesions in live cells expressing GFP-tagged vinculin. Local forces are correlated with the ...

A group of researchers led by Dr. He Kangmin from the Institute of Genetics and Developmental Biology and Dr. Fang Xiaohong from Hangzhou Institute of Medicine, has identified focal adhesions as ...

Focal adhesions are known as signalling platforms broadcasting the information of the biochemical and physical qualities of the extracellular matrix into intracellular signalling cascades.

Focal adhesions are known as signaling platforms broadcasting the information of the biochemical and physical qualities of the extracellular matrix into intracellular signaling cascades.

Imaging studies implicate microtubule targeting of focal adhesions in focal adhesion disassembly, although the molecular mechanism is unknown. Here, we develop a model system of focal adhesion ...

Even more fascinating is the intricate relationship between lysosomal exocytosis and focal adhesions, structures critical for ...

This screen shot of a migrating human skin cell shows focal adhesion sites with which cells attach to the extracellular matrix in purple, and receptors that link microtubules to focal adhesions in two ...

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Verastem will present data on the targeted inhibition of Focal Adhesion Kinase (FAK) in mesothelioma. Approximately 50% of patients with mesothelioma harbor a specific genetic lesion in the gene ...