However, focal adhesions remain unstudied in the context of human pluripotent stem cells. The research group led by Academy Professor Johanna Ivaska from the Turku Bioscience Centre at the University ...

We are interested in the molecular mechanisms connecting the focal adhesions to transcriptional regulation of pluripotency," says Academy Professor Johanna Ivaska from the Turku Bioscience Centre.

Focal adhesions are known as signalling platforms broadcasting the information of the biochemical and physical qualities of the extracellular matrix into intracellular signalling cascades. However ...

Focal adhesion kinase inhibition as a therapeutic strategy in differentiated thyroid cancer. Authors: Shalana O'Brien, Vita Golubovskaya, Maria Zajac-Kaye, Steven N. Hochwald, and William G. Cance ...

Focal Adhesion Kinase as a Therapeutic Target for Meningiomas With Somatic Neurofibromatosis Type 2 Mutations The following represents disclosure information provided by the author of this manuscript.

Immunofluorescence image showing S100A11 (green) localization to focal adhesions and actin stress fibers in a HeLa cell. Microtubules are labeled in red. Researchers at Kanazawa University report ...

BioWorld Content on 'focal adhesion kinase'Pretreatment with an experimental focal adhesion kinase inhibitor has been shown to improve chemotherapeutic efficiency and reduce metastasis in preclinical ...

This connection is mediated by multi-protein complexes called focal adhesions. A critical component of focal adhesions is integrin, a transmembrane-receptor protein. “The mechanism for integrin ...

The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal ...

Focal adhesions are known as signaling platforms broadcasting the information of the biochemical and physical qualities of the extracellular matrix into intracellular signaling cascades. However ...