Hierarchical tricarboxylic acid cycle regulation by hepatocyte arginase 2 links the urea cycle to oxidative metabolism. Cell Metabolism, 2024; DOI: 10.1016/j.cmet.2024.07.007 ...

In a 2022 Cell Reports Medicine study, DeBosch and his team found that administering an enzyme called pegylated arginine deiminase (ADI-PEG 20) significantly improved symptoms of fatty liver and ...

In a 2022 Cell Reports Medicine study, DeBosch and his team found that administering an enzyme called pegylated arginine deiminase (ADI-PEG 20) significantly improved symptoms of fatty liver and ...

New research explores the urea cycle’s strong connection to fatty liver disease Peer-Reviewed Publication Indiana University School of Medicine ...

Clinical Investigation Published: July 2009 Article Intellectual, Adaptive, and Behavioral Functioning in Children With Urea Cycle Disorders Lauren Krivitzky, Talin Babikian, Hye-Seung Lee, Nina ...

HealthDay News — The FDA has approved glycerol phenylbutyrate (Ravicti, Hyperion Therapeutics) to treat certain urea cycle disorders (UCDs) in patients aged 2 years and older.

The Food and Drug Administration (FDA) has accepted for filing the New Drug Application for ACER-001 (sodium phenylbutyrate) for the treatment of patients with urea cycle disorders. ACER-001, a ...