Recently, researchers at Tokyo University of Science (TUS) identified a promising tyrosinase inhibitor from Corynebacterium tuberculostearicum (C. tuberculostearicum), a bacterium commonly found ...

Journal of enzyme inhibition and medicinal chemistry (ISSN: 1475-6366, 1475-6374) ...

Using docking simulations, recent study found that cyclo (L-Pro-L-Tyr) binds to the substrate-binding site of mushroom tyrosinase, obstructing the substrate pocket and preventing its activity.

However, only molecular docking has proven useful for identifying protein-ligand interactions and the mechanism (s) of action of a drug. Although versatile, docking requires prior knowledge of the ...