Many animals, including humans, can flexibly modulate their responsiveness to sounds according to different situations. This ...

So far, researchers have identified seven distinct types of dopamine neurons by looking at their genetic profiles. A study published in August 2023 was the first to parse dopamine function based ...

But in the 1970s, the discovery of dopamine receptors in the brain led to an important realization: haloperidol binds to and blocks a certain type of dopamine receptor, suggesting that dopamine ...

“Without these neurons, the entire brain systems under dopamine control would become overactive and uncontrollable, since they act to balance the functions of the two types of dopamine receptors in ...

Striatal projection neurons coexpressing dopamine D1 and D2 receptors modulate the motor function of D1- and D2-SPNs. Nature Neuroscience, 2024; DOI: 10.1038/s41593-024-01694-4 ...

Dopamine receptor deficiency also has been documented in individuals addicted to various types of drugs including cocaine, alcohol, and opiates.