Investigating chromatin's 3D architecture reveals its influence on gene regulation, shedding light on mechanisms underlying cancer and muscular dystrophy.

"How these two types of chromatin are organized and behave inside living cells is still not well understood," says Katsuhiko Minami, the first author of this study. "Until now, we lacked a way to ...

More information: Luay M. Almassalha et al, Chromatin conformation, gene transcription, and nucleosome remodeling as an emergent system, Science Advances (2025). DOI: 10.1126/sciadv.adq6652 ...

"How these two types of chromatin are organized and behave inside living cells is still not well understood," says Katsuhiko Minami, the first author of this study.