Using a new animal model of Alzheimer’s disease, the study highlights a potential breakthrough in treatment strategies.

A new study published in Brain, Behavior, and Immunity has found that inflammation in a key memory center of the brain can change motivated behavior in mice, and these changes occur differently in ...

A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the ...

A model for hepatitis B virus-associated chronic ... Figure 2: Concentration of HBV DNA in the sera of transgenic mice. Figure 3: Detection of viral antigens in the serum and liver of transgenic ...

Creating transgenic rodent models requires transgenesis: the introduction of exogenous DNA sequences into the genome, typically to drive protein expression in a specific spatial or temporal way.

TASTPM is a double transgenic mouse model of Alzheimer’s disease carrying two mutations associated with early onset disease: the Swedish mutation in APP and the M146V mutation in PSEN1. The double ...

A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the two key pathological ...

A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the ...

This breakthrough was made possible by the development of a novel transgenic mouse model that replicates both tau and beta-amyloid pathologies. "Although both proteins accumulate in the brains of ...