PinCell, a biotechnology company developing a first-in-class therapy for rare and debilitating autoimmune skin blistering diseases, has announced the generation of a transgenic mouse model that ...

Reference: Ye J, Xu Y, Ren Q, Liu L, Sun Q. Nutrient deprivation induces mouse embryonic diapause mediated by Gator1 and Tsc2. Development. 2024. doi: 10.1242/dev.202091 This article has been ...

Around 200 of a mouse’s genes are imprinted, but Li’s team focused on 20 that are known to be important for the development of the embryo. In an attempt to create healthy mice with DNA from ...

Once the resulting embryo had grown large enough, the team put it into the uterus of a foster-mother mouse in the hope a pregnancy would ensue. Out of 259 bipaternal embryos transferred into 18 ...