Transduction efficiency (i.e., how much of the genetic material from the packaged lentivirus is transferred and incorporated into the cell) can vary widely. Microfluidics-driven solution ...

A man with long-standing type 1 diabetes underwent transplant with UP421 gene-edited islet cells designed to avoid rejection.

On July 14, 2025, Professor Su Xiaodong’s team from the School of Life Sciences at Peking University, in collaboration with Professor John Rasko’s team from the University of Sydney, published a ...

Hansa Biosciences’ Idefirix (imlifidase) has reduced patients’ antibodies to a level that allows dosing in patients with ...

To improve the efficacy of gene therapy when using anti-sickling beta globin gene transfer, they added cyclosporin (CsH) to increase transduction by inhibiting lentiviral restriction factors.

Myocardial transduction was observed, with a median myocardial vector copy number per diploid nucleus of 0.251 (range, 0.042 to 1.36) and median LAMP2B transcript copies per μg RNA of 3.72×10 5 ...