February 1, 2006 (Vol. 26, No. 3) Using Transcription Factor Probes to Discover Unknown Signal Pathways Marligen Biosciences (www. marligen.com) has developed assays that allow researchers to ...

Moreover, the assay clarified that in most cases the regulatory motifs determined whether transcription was enhanced or dampened, but the timing of the perturbation determined the magnitude of the ...

Over the last several years the identification and functional characterization of the motor proteins actin and myosin in the nucleus has initiated a change in the view of nuclear processes. It is now ...

LMO2 is an intrinsically disordered transcription factor activated in T cell leukaemia that is difficult to target. It forms part of a multiprotein complex that has bipartite DNA binding through ...

Marilyn Vaccaro, Andre Pawlak, Jean-Pierre Jost, Positive and Negative Regulatory Elements of Chicken Vitellogenin II Gene Characterized by in vitro Transcription Competition Assays in a Homologous ...

Glioma is an aggressive and malignant brain tumor with a poor prognosis, accounting for nearly half of all primary malignant ...

According to Y1H and Dual-LUC assays, CmMYB012 interacted with the promoters of CmCHS, CmDFR, CmANS, and CmUFGT to inhibit their transcription, thereby reducing anthocyanin content.

French contract research organization (CRO) Cytoo specializes in developing high-content, three-dimensional cellular assays for muscle and skin. It does so by means of micropatterns, which are ...

The recent explosion in the sample sizes and diversity of omics assays has created exciting new opportunities for biomedical scientists. However, connecting these omics data types in an interpretable ...

Here, we describe a simple test for detection of SARS-CoV-2. The sensitivity of this test is similar to that of reverse-transcription–quantitative polymerase-chain-reaction (RT-qPCR) assays.