The addition of temozolomide to radiation therapy prolonged OS for patients with both co-deleted and non-co-deleted grade 2 gliomas, according to study results.These are the first data from a ...

Both radiation and temozolomide, a generic chemotherapy treatment in pill form, have meaningful single-modality anti-tumor activity against slow-growing, low-grade gliomas. The randomized phase 3 ...

Key Takeaways Veliparib addition to temozolomide did not significantly extend overall survival in MGMT-hypermethylated glioblastoma patients. The investigational combination was well tolerated, with ...

Key Takeaways Concomitant radiotherapy with temozolomide significantly improves PFS in IDH-wildtype glioblastoma patients compared to radiotherapy alone. The study involved 244 patients, with 72.5% ...

Yumanity Therapeutics (NASDAQ: YMTX) has announced results from preclinical studies of YTX-7739 in glioblastoma multiforme (GBM). Researchers at the Massachusetts General Hospital conducted the study.

This trial compared temozolomide (Temodal) with PCV for a type of brain tumour called glioma. This trial was open to people whose glioma had come back after treatment. This trial was supported by ...

For glioblastoma multiforme (GBM), the median estimate of progression‑free survival, using temozolomide was 12.4 weeks, and using procarbazine, 8.3 weeks (a difference of 4.1 weeks, p=0.006). The ...

This trial compared radiotherapy alone with radiotherapy and temozolomide for a type of brain tumour called anaplastic glioma. This trial was supported by Cancer Research UK. Anaplastic glioma is a ...

Temozolomide is commonly used to treat certain brain cancers, including glioblastoma and anaplastic astrocytoma. Temozolomide may also be used for other conditions as determined by your healthcare ...

1 Guidance 1.1 Temozolomide is recommended as an option for treating malignant glioma, such as glioblastoma multiforme or anaplastic astrocytoma, showing recurrence or progression after standard ...