Researchers at The University of Texas MD Anderson Cancer Center have identified a potential breakthrough in the fight ...

After years of hard work, scientists have succeeded in creating genetically-engineered mice that could help accelerate ...

Globally, scientists are working to unlock the secrets of extending human lifespan at the cellular level, where aging occurs ...

Telomerase is a ribonucleoprotein enzyme that maintains the protective structures at the ends of eukaryotic chromosomes, called telomeres. In most human somatic cells, telomerase expression is ...

Researchers have developed HuT mice, a genetically engineered model with human-like telomeres, enabling scientists to study ...

The mouse model in the study is reportedly quite different as it allows scientists to observe the aging process in a whole ...

Continually proliferating cells maintain adequate telomeres through the action of the reverse transcriptase telomerase. Telomeres are important to human health because dysregulation of either telomere ...

Normally mice have telomeres that are up to 10 times longer than humans. This is the first mouse model with truly humanized telomeres because telomerase isn't expressed in adult tissues in this model.

A briefing document (PDF) published by the FDA reviewer ahead of the adcomm has questioned the efficacy seen with the telomerase inhibitor, suggesting that the data doesn’t point to a disease ...

The three were honored for “for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase.” According to the Royal Swedish Academy, this year’s Nobel Prize in Physiology or ...

Our first-in-class telomerase inhibitor RYTELO® (imetelstat) is approved in the United States for the treatment of certain adult patients with lower-risk myelodysplastic syndromes (LR-MDS ...