Personalised medicine is already a reality in clinical practice, and CAR-T cell therapy is one of its most promising tools. This innovative approach, which involves genetically modifying the cells ...

CAR T-cell therapy has the potential to revolutionise how we treat certain types of cancer by genetically engineering someone’s own immune cells to attack the disease – but it is also ...

A new study in cats with a fatal coronavirus infection suggests stem cell therapy could help tackle the immune damage behind severe COVID-19 and long COVID.

In CAR T-cell therapy, doctors take these T-cells from a person’s blood (a process known as leukapheresis) and modify them in a lab so they can recognise and destroy cancer cells more effectively.

CAR-T-Cell Therapies At present, six CAR-T-cell therapies have been approved by the European Commission and the US Food and Drug Administration (FDA). The CAR-T-cell products targeting CD19 are ...

Malignant T-cell transformation after chimeric antigen receptor (CAR) T-cell therapy has been described, but the contribution of CAR integration to oncogenesis is not clear. Here we report a case o ...