Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of drug ...

These validation techniques exhibit the potential to kinetically image and measure immune cell-induced toxicity ... assays enable the analysis of advanced tumor spheroid models like CAR-T mediated ...

A major theme running through Visiongain’s recent London-based “Cell Based Assays ... aren’t likely to be seen at greater than 10 micromolars, “as a rule any toxicity we pick up at ...

During a live event, Nathan M. Denlinger, DO, MS, discussed the PILOT and ALYCANTE trials of CAR T-cell therapy in transplant ...

Characterization of antigen-specific T cell responses typically is a critical constituent of these immunological investigations which can also aid in patient stratification for future trials. As a ...

CAR T-cell therapies have ... remains a challenge. 3D cell culture models are essential in researching how therapies can infiltrate and remain effective in solid tumor microenvironments. By optimizing ...

Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg have identified a previously undocumented, organ-specific ...

CAR T cell therapy against CD19 and B cell maturation antigen (BCMA) is a potent immunotherapy for treating advanced B cell malignancies. It comes with a unique toxicity profile that includes cytokine ...