The substantia nigra anatomy is made up of two parts: the pars compacta (SNpc) and the pars reticulata (SNpr). Pars compacta. The SNpc is responsible for releasing dopamine to the striatum ...

Parkinson's disease is a chronic progressive neurological disease that affects a small area of nerve cells (neurons) in an area of the brain known as the substantia nigra. These cells normally ...

Iron content is increased in the substantia nigra of persons with Parkinson ... to the intention-to-treat principle with the use of a two-sided test with a significance level of 0.05.

For the first time, researchers have sorted large numbers of human brain cells in the substantia nigra into 10 distinct types. Just one is especially vulnerable in Parkinson’s disease ...

This is exactly what Eric Vilain and colleagues at the University of California, Los Angeles, have discovered about dopaminergic neurons in the substantia nigra (SN ... silenced the gene by infusing ...

The focus of the disease is the progressive degeneration of dopamine-producing nerve cells in a certain region of the midbrain, the substantia nigra ... In the last two decades, researchers ...

In a recent study published in Progress in Neurobiology, researchers discover that the substantia nigra of individuals ... and pheomelanin moieties derived from a two-to-one ratio of dopamine ...

About The Study: In this cross-sectional study of contact sports athletes with chronic traumatic encephalopathy (CTE), years of contact sports participation were associated with substantia nigra ...