Their study shows inhibition of a critical human enzyme: autotaxin. Researchers used crystallographic data to determine THC's structure when bound with autotaxin, which is responsible for ...

The image of the human cannabinoid receptor 1 (CB1) and its binding site for the chemical THC should lead to a better understanding of how marijuana affects the brain, UT Southwestern says.

Finally, the researchers did computer simulations of how CB1 would interact with molecules like THC. Basically, you program the receptor and molecule into the computer and tell it to figure out ...