Structural variation refers to alterations in the structure of an organism’s genome, such as deletions, duplications, and inversions of the genetic sequence.

Mapping the Genome’s 3D Structure The research team discovered that the genome arranges itself into two distinct compartments: one active and accessible, the other more tightly packed and inactive.

The Human Genome Project, presented in its final form 10 years ago this month, opened up a Pandora’s box of boggling complexity.

Cold sore-causing HSV-1 doesn't just hijack cells it reconfigures the entire architecture of our DNA to aid its invasion. Researchers discovered that it actively reshapes the 3D structure of the ...

Quirks and Quarks 54:02 New human genome, lion cuddle chemical, Pluto’s ice volcanoes, deconstructing de-extinction, giant crocodiles in BC ...

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

The relationship between activity and structure might be a two-way street," says Dr. Álvaro Castells García, co-first author of the study. Two in every three people under age 50 live with HSV-1.

It’s a marvel how the human genome — two meters of DNA — fits into the tiny nucleus of a cell while orchestrating the complex processes that sustain life. A new study from Northwestern Engineering’s ...

Food contains more than 139,000 molecules, which influence nearly half the human proteome. Systematic analysis of food–chemical interactions can potentially advance nutrition science and drug ...